The One Health EJP Final School 2022 with the theme “Sustainability in One Health: how can it be achieved?” is an online event. Over the last 5 years, the One Health EJP has facilitated transdisciplinary and cross-sector research collaborations to better prevent, predict, detect and respond to the global health threats of antimicrobial resistance, foodborne zoonoses and emerging zoonotic diseases. This event aims to communicate how our programme’s outcomes can further advance One Health.