To celebrate One Health Day 2023, the Nossal Institute for Global Health is hosting a panel of experts to collectively address the increasing health, food security, water, energy and biodiversity challenges the world faces. Professor Tim Flannery, Climate Council; Dr Rachel Iglesias, Office of the Chief Veterinary Officer, Department of Agriculture, Forestry and Fisheries; Professor Benjamin Cowie, Acting Chief Health Officer, Victoria; and Associate Professor Angus Campbell, Nossal Institute for Global Health, will bring their unique perspectives on One Health action.