Instituto de Ciências Biomédicas Abel Salazar (ICBAS) is organizing, together with several Research Units, a conference to celebrate the International One Health Day. With this event, scheduled for November 3rd, 2021, we intend to raise awareness and educate about the challenges of human, animal, and environmental health, and reinforce the need for collaboration between different professionals and disciplines. The talks of the '1st Porto One Health Day' will have a hybrid format: face-to-face, from different places, but will also be transmitted through the Zoom platform.